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miR-34a repression of SIRT1 regulates apoptosis
MicroRNA 34a (miR-34a) is a tumor suppressor gene, but how it regulates cell proliferation is not completely understood. We now show that the microRNA miR-34a regulates silent information regulator 1 (SIRT1) expression. MiR-34a inhibits SIRT1 expression through a miR-34a-binding site within the 3′ U...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533205/ https://ncbi.nlm.nih.gov/pubmed/18755897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801613105 |
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