A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis

BACKGROUND: The difficulty in elucidating the genetic basis of complex diseases roots in the many factors that can affect the development of a disease. Some of these genetic effects may interact in complex ways, proving undetectable by current single-locus methodology. RESULTS: We have developed an...

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Detalhes bibliográficos
Main Authors: Gayán, Javier, González-Pérez, Antonio, Bermudo, Fernando, Sáez, María Eugenia, Royo, Jose Luis, Quintas, Antonio, Galan, Jose Jorge, Morón, Francisco Jesús, Ramirez-Lorca, Reposo, Real, Luis Miguel, Ruiz, Agustín
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533022/
https://ncbi.nlm.nih.gov/pubmed/18667089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-360
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