Methylation alterations are not a major cause of PTTG1 missregulation

BACKGROUND: On its physiological cellular context, PTTG1 controls sister chromatid segregation during mitosis. Within its crosstalk to the cellular arrest machinery, relies a checkpoint of integrity for which gained the over name of securin. PTTG1 was found to promote malignant transformation in 3T3...

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Autori principali: Hidalgo, Manuel, Galan, Jose Jorge, Sáez, Carmen, Ferrero, Eduardo, Castilla, Carolina, Ramirez-Lorca, Reposo, Pelaez, Pablo, Ruiz, Agustin, Japón, Miguel A, Royo, Jose Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377271/
https://ncbi.nlm.nih.gov/pubmed/18426563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-110
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