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The stacking tryptophan of galactose oxidase: a second coordination sphere residue that has profound effects on tyrosyl radical behavior and enzyme catalysis

The function of the stacking tryptophan, W290, a second coordination sphere residue in galactose oxidase has been investigated via steady-state kinetics measurements, absorption, CD and EPR spectroscopy, and x -ray crystallography of the W290F, W290G, and W290H variants. Enzymatic turnover is signif...

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書誌詳細
主要な著者: Rogers, Melanie S., Tyler, Ejan M., Akyumani, Nana, Kurtis, Christian R., Spooner, R. Kate, Deacon, Sarah E., Tamber, Sunita, Firbank, Susan J., Mahmoud, Khaled, Knowles, Peter F., Phillips, Simon E. V., McPherson, Michael J., Dooley, David M.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532978/
https://ncbi.nlm.nih.gov/pubmed/17385891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062139d
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