The stacking tryptophan of galactose oxidase: a second coordination sphere residue that has profound effects on tyrosyl radical behavior and enzyme catalysis

The function of the stacking tryptophan, W290, a second coordination sphere residue in galactose oxidase has been investigated via steady-state kinetics measurements, absorption, CD and EPR spectroscopy, and x -ray crystallography of the W290F, W290G, and W290H variants. Enzymatic turnover is signif...

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Bibliografiska uppgifter
Huvudupphovsmän: Rogers, Melanie S., Tyler, Ejan M., Akyumani, Nana, Kurtis, Christian R., Spooner, R. Kate, Deacon, Sarah E., Tamber, Sunita, Firbank, Susan J., Mahmoud, Khaled, Knowles, Peter F., Phillips, Simon E. V., McPherson, Michael J., Dooley, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532978/
https://ncbi.nlm.nih.gov/pubmed/17385891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062139d
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