MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus

Infection by RNA viruses is detected by the host through Toll-like receptors or RIG-I-like receptors. Toll-like receptors and RIG-I-like receptors signal through the adaptors MyD88 and MAVS, respectively, to induce type I IFNs (IFN-I) and other antiviral molecules, which are thought to be essential...

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Detalhes bibliográficos
Main Authors: Bhoj, Vijay G., Sun, Qinmiao, Bhoj, Elizabeth J., Somers, Cynthia, Chen, Xiang, Torres, Juan-Pablo, Mejias, Asuncion, Gomez, Ana M., Jafri, Hasan, Ramilo, Octavio, Chen, Zhijian J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532974/
https://ncbi.nlm.nih.gov/pubmed/18780793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804717105
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