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Measurement of the Incorporation and Repair of Exogenous 5-Hydroxymethyl-2′-deoxyuridine in Human Cells in Culture Using Gas Chromatography-Negative Chemical Ionization-Mass Spectrometry

The DNA of all organisms is constantly damaged by oxidation. Among the array of damage products is 5-hydroxymethyluracil, derived from oxidation of the thymine methyl group. Previous studies have established that HmU can be a sensitive and valuable marker of DNA damage. More recently, the correspond...

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Autori principali: Rogstad, Daniel K., Darwanto, Agus, Herring, Jason L., Rogstad, Katherine Noyes, Burdzy, Artur, Hadley, Scott, Neidigh, Jonathan W., Sowers, Lawrence C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532841/
https://ncbi.nlm.nih.gov/pubmed/17914883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700221x
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