Efficient generation of human alloantigen-specific CD4(+) regulatory T cells from naive precursors by CD40-activated B cells

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Treg) play an important role in the induction and maintenance of immune tolerance. Although adoptive transfer of bulk populations of Treg can prevent or treat T cell–mediated inflammatory diseases and transplant allograft rejection in animal models, optimal...

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Main Authors: Tu, Wenwei, Lau, Yu-Lung, Zheng, Jian, Liu, Yinping, Chan, Ping-Lung, Mao, Huawei, Dionis, Kira, Schneider, Pascal, Lewis, David B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2008
Ábhair:
Transplantation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532818/
https://ncbi.nlm.nih.gov/pubmed/18599794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-152041
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