Somatic ‘Soluble’ Adenylyl Cyclase Isoforms Are Unaffected in Sacy(tm1Lex)/Sacy(tm1Lex) ‘Knockout’ Mice

BACKGROUND: Mammalian Soluble adenylyl cyclase (sAC, Adcy10, or Sacy) represents a source of the second messenger cAMP distinct from the widely studied, G protein-regulated transmembrane adenylyl cyclases. Genetic deletion of the second through fourth coding exons in Sacy(tm1Lex)/Sacy(tm1Lex) knocko...

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Autori principali: Farrell, Jeanne, Ramos, Lavoisier, Tresguerres, Martin, Kamenetsky, Margarita, Levin, Lonny R., Buck, Jochen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532759/
https://ncbi.nlm.nih.gov/pubmed/18806876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003251
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