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Development of a fluorescent substrate to measure hyaluronidase activity

A novel fluorescent substrate (termed FRET-HA) to quantitatively assess hyaluronidase activity was developed. Hyaluronan (HA), the major substrate for hyaluronidase, was dual labeled with fluorescein amine and rhodamine B amine. The fluorescein amine fluorescence signal was significantly quenched wh...

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Detalhes bibliográficos
Main Authors: Zhang, Li-Shu, Mummert, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532756/
https://ncbi.nlm.nih.gov/pubmed/18492482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.04.040
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