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Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch

Applications of conditional gene expression, whether for therapeutic or basic research purposes, are increasingly requiring mammalian gene control systems that exhibit far tighter control properties. While numerous approaches have been used to improve the widely used Tet-regulatory system, many appl...

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Bibliografiske detaljer
Main Authors: Greber, David, El-Baba, Marie Daoud, Fussenegger, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532736/
https://ncbi.nlm.nih.gov/pubmed/18632760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn443
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