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Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch

Applications of conditional gene expression, whether for therapeutic or basic research purposes, are increasingly requiring mammalian gene control systems that exhibit far tighter control properties. While numerous approaches have been used to improve the widely used Tet-regulatory system, many appl...

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Detalles Bibliográficos
Main Authors: Greber, David, El-Baba, Marie Daoud, Fussenegger, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532736/
https://ncbi.nlm.nih.gov/pubmed/18632760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn443
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