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Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch

Applications of conditional gene expression, whether for therapeutic or basic research purposes, are increasingly requiring mammalian gene control systems that exhibit far tighter control properties. While numerous approaches have been used to improve the widely used Tet-regulatory system, many appl...

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Bibliografische gegevens
Hoofdauteurs: Greber, David, El-Baba, Marie Daoud, Fussenegger, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532736/
https://ncbi.nlm.nih.gov/pubmed/18632760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn443
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