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Hyperthermophilic Aquifex aeolicus initiates primer synthesis on a limited set of trinucleotides comprised of cytosines and guanines

The placement of the extreme thermophile Aquifex aeolicus in the bacterial phylogenetic tree has evoked much controversy. We investigated whether adaptations for growth at high temperatures would alter a key functional component of the replication machinery, specifically DnaG primase. Although the s...

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Detalhes bibliográficos
Main Authors: Larson, Marilynn A., Bressani, Rafael, Sayood, Khalid, Corn, Jacob E., Berger, James M., Griep, Mark A., Hinrichs, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532735/
https://ncbi.nlm.nih.gov/pubmed/18684998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn461
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