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Conformational changes below the T(m): Molecular dynamics studies of the thermal pretransition of ribonuclease A

Recent work suggests that some native conformations of proteins can vary with temperature. To obtain an atomic-level description of this structural and conformational variation, we have performed all-atom, explicit-solvent molecular dynamics simulations of bovine pancreatic ribonuclease A (RNase A)...

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Detalhes bibliográficos
Main Authors: Merkley, Eric D., Bernard, Brady, Daggett, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532537/
https://ncbi.nlm.nih.gov/pubmed/18161991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701565b
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