Enantioselective TADMAP-Catalyzed Carboxyl Migration Reactions for the Synthesis of Stereogenic Quaternary Carbon

The chiral, nucleophilic catalyst TADMAP (1) has been prepared from 3-lithio-4-dimethylamino-pyridine (5) and triphenylacetaldehyde (3), followed by acylation and resolution. TADMAP catalyzes the carboxyl migration of oxazolyl, furanyl, and benzofuranyl enol carbonates with good to excellent levels...

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Auteurs principaux: Shaw, Scott A., Aleman, Pedro, Christy, Justin, Kampf, Jeff W., Va, Porino, Vedejs, Edwin
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532525/
https://ncbi.nlm.nih.gov/pubmed/16417383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056150x
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