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Cofactor-Dependence in Reduction Potentials for [4Fe–4S](2+/1+) in Lysine 2,3-Aminomutase

Lysine 2,3-aminomutase (LAM) catalyzes the interconversion of l-lysine and l-β-lysine by a free radical mechanism. The 5′-deoxyadenosyl radical derived from the reductive cleavage of S-adenosyl-l-methionine (SAM) initiates substrate-radical formation. The [4Fe–4S](1+) cluster in LAM is the one-elect...

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Bibliografski detalji
Glavni autori: Hinckley, Glen T., Frey, Perry A.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532065/
https://ncbi.nlm.nih.gov/pubmed/16519516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0519497
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