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A chronic carrierlike state is established in nude mice injected with cloned hepatitis B virus DNA.

BALB/c nude mice were injected intrahepatically with hepatitis B virus (HBV) DNA prepared from recombinant plasmids. Hepatitis B surface antigen appeared in the circulation in 19 of 23 mice (82%) 3 to 20 weeks postinjection and persisted for more than 6 months in most animals. Hepatitis B e antigen...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Feitelson, M A, DeTolla, L J, Zhou, X D
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3346949/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.4.1408-1415.1988
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