A chronic carrierlike state is established in nude mice injected with cloned hepatitis B virus DNA.

BALB/c nude mice were injected intrahepatically with hepatitis B virus (HBV) DNA prepared from recombinant plasmids. Hepatitis B surface antigen appeared in the circulation in 19 of 23 mice (82%) 3 to 20 weeks postinjection and persisted for more than 6 months in most animals. Hepatitis B e antigen...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Feitelson, M A, DeTolla, L J, Zhou, X D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3346949/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.4.1408-1415.1988
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