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Purification and crystallization of a non-GluR2 AMPA-receptor ligand-binding domain: a case of cryo-incompatibility addressed by room-temperature data collection

Glutamate is the major excitatory neurotransmitter in the brain. Among the cognate ionotropic glutamate receptors, the subfamily selective for AMPA (α-­amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) is responsible for most fast excitatory synaptic signaling and plays key roles in synaptic plas...

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Hlavní autoři: Gill, Avinash, Madden, Dean R.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531279/
https://ncbi.nlm.nih.gov/pubmed/18765917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108025426
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