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Optical Imaging of Bacterial Infection in Living Mice Using a Fluorescent Near-Infrared Molecular Probe

An optical imaging probe was synthesized by attaching a near-infrared carbocyanine fluorophore to an affinity group containing two zinc(II) dipicolylamine (Zn-DPA) units. The probe has a strong and selective affinity for the surfaces of bacteria, and it was used to image infections of Gram-positive...

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Detalhes bibliográficos
Main Authors: Leevy, W. Matthew, Gammon, Seth T., Jiang, Hua, Johnson, James R., Maxwell, Dustin J., Jackson, Erin N., Marquez, Manuel, Piwnica-Worms, David, Smith, Bradley D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531239/
https://ncbi.nlm.nih.gov/pubmed/17177377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0665592
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