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An Efficient Synthesis of 5-Amido-3-Hydroxy-4-Pyrones as Inhibitors of Matrix Metalloproteinases

[Image: see text] 3-Hydroxy-4-pyrones are a class of important metal chelators with versatile medicinal applications. An efficient pathway for the preparation of new 5-amido-3-hydroxy-4-pyrone derivatives has been developed. The synthesized 5-amido-3-hydroxy-4-pyrones have been evaluated as inhibito...

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Detalhes bibliográficos
Main Authors: Yan, Yi-Long, Cohen, Seth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531216/
https://ncbi.nlm.nih.gov/pubmed/17521196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0707665
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