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Recurrence of Autoreactive Antigen-specific CD4+ T Cells in Autoimmune Diabetes after Pancreas Transplantation

CD4+ T cells specific for the diabetes-associated autoantigen GAD65 were analyzed using peripheral blood samples after pancreas transplantation in subjects with T1D with clinical evidence of recurrent autoimmune diabetes. MHC class II tetramers facilitated the identification and cloning of antigen-s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Laughlin, Elsa, Burke, George, Pugliese, Alberto, Falk, Ben, Nepom, Gerald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531116/
https://ncbi.nlm.nih.gov/pubmed/18455963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.03.459
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