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Site-specific alteration of murine hepatitis virus type 4 peplomer glycoprotein E2 results in reduced neurovirulence.

Strains of the murine coronavirus mouse hepatitis virus type 4 (MHV-4) which contained a mutation in the E2 peplomer glycoprotein were obtained by selection for resistance to neutralization by monoclonal antibodies. Characterization of six variants representing two independent epitopes on E2, E2B an...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:J Virol
Ngā kaituhi matua: Dalziel, R G, Lampert, P W, Talbot, P J, Buchmeier, M J
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology (ASM) 1986
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016306/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.59.2.463-471.1986
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