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RNA recombination of coronaviruses: localization of neutralizing epitopes and neuropathogenic determinants on the carboxyl terminus of peplomers.
Murine coronaviruses undergo RNA recombination at a very high frequency. We have obtained a series of recombinant viruses using neutralizing monoclonal antibodies in conjunction with temperature-sensitive markers. All of the recombinants obtained have a crossover within gene C, which encodes the pep...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
1987
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299120/ https://ncbi.nlm.nih.gov/pubmed/2442761 |
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