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Synthesis, Antifungal Activity, and Structure Activity Relationships of Coruscanone A Analogs

Coruscanone A, a plant derived cyclopentenedione derivative, showed potent in vitro antifungal activity against Candida albicans and Cryptococcus neoformans, comparable to amphotericin B and fluconazole. A series of analogs have been synthesized by modification of the cyclopentenedione ring, the eno...

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Detalhes bibliográficos
Main Authors: Babu, K. Suresh, Li, Xing-Cong, Jacob, Melissa R., Zhang, Qifeng, Khan, Shabana I., Ferreira, Daneel, Clark, Alice M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2530892/
https://ncbi.nlm.nih.gov/pubmed/17181171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm061123i
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