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SELECTION OF ANTHRAX TOXIN PROTECTIVE ANTIGEN VARIANTS THAT DISCRIMINATE BETWEEN THE CELLULAR RECEPTORS TEM8 AND CMG2 AND ACHIEVE TARGETING OF TUMOR CELLS
Anthrax toxin, a three-component protein toxin secreted by Bacillus anthracis, assembles into toxic complexes at the surface of receptor-bearing eukaryotic cells. The protective antigen (PA) protein binds to receptors, either tumor endothelial cell marker 8 (TEM8) or capillary morphogenesis protein...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2530824/ https://ncbi.nlm.nih.gov/pubmed/17251181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611142200 |
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