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SELECTION OF ANTHRAX TOXIN PROTECTIVE ANTIGEN VARIANTS THAT DISCRIMINATE BETWEEN THE CELLULAR RECEPTORS TEM8 AND CMG2 AND ACHIEVE TARGETING OF TUMOR CELLS

Anthrax toxin, a three-component protein toxin secreted by Bacillus anthracis, assembles into toxic complexes at the surface of receptor-bearing eukaryotic cells. The protective antigen (PA) protein binds to receptors, either tumor endothelial cell marker 8 (TEM8) or capillary morphogenesis protein...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Kuang-Hua, Liu, Shihui, Bankston, Laurie A., Liddington, Robert C., Leppla, Stephen H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2530824/
https://ncbi.nlm.nih.gov/pubmed/17251181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611142200
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