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Functional Evaluation of Conserved Basic Residues in Human Phosphomevalonate Kinase.
Phosphomevalonate kinase (PMK) catalyzes the cation dependent reaction of mevalonate 5-phosphate with ATP to form mevalonate 5-diphosphate and ADP, a key step in the mevalonate pathway for isoprenoid/sterol biosynthesis. Animal PMK proteins belong to the nucleoside monophosphate (NMP) kinase family....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2530820/ https://ncbi.nlm.nih.gov/pubmed/17902708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701408t |
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