Replication and resolution of cloned poxvirus telomeres in vivo generates linear minichromosomes with intact viral hairpin termini.

The covalently closed terminal hairpins of the linear duplex-DNA genomes of the orthopoxvirus vaccinia and the leporipoxvirus Shope fibroma virus (SFV) have been cloned as imperfect palindromes within circular plasmids in yeast cells and recombination-deficient Escherichia coli. The viral telomeres...

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Veröffentlicht in:	J Virol
Hauptverfasser:	DeLange, A M, Reddy, M, Scraba, D, Upton, C, McFadden, G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.59.2.249-259.1986
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