Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing).

In this paper we provide a step by step comparison of the pathogenesis of murine infection caused by reovirus type 3 (Dearing) and an antigenic variant (K) selected by its resistance to neutralization with a monoclonal antibody (G5) directed against the T3 hemagglutinin. To show that specific change...

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Bibliographic Details
Main Authors: Kaye, K M, Spriggs, D R, Bassel-Duby, R, Fields, B N, Tyler, K L
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC253042/
https://ncbi.nlm.nih.gov/pubmed/3012122
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