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Virulence of La Crosse virus is under polygenic control.

To identify which RNA segments of the California serogroup bunyaviruses determine virulence, we prepared reassortant viruses by coinfecting BHK-21 cells with two wild-type parents, La Crosse/original and Tahyna/181-57 viruses, which differed about 30,000-fold in virulence. The progeny clones were sc...

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Detalhes bibliográficos
Main Authors: Janssen, R S, Nathanson, N, Endres, M J, Gonzalez-Scarano, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC253030/
https://ncbi.nlm.nih.gov/pubmed/3712554
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