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An avirulent G1 glycoprotein variant of La Crosse bunyavirus with defective fusion function.

La Crosse virus, a member of the California serogroup of the family Bunyaviridae, causes encephalitis in humans and laboratory rodents. A variant virus (V22) selected with a monoclonal antibody against the large (G1) glycoprotein showed diminished neuroinvasiveness after peripheral inoculation. This...

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Detalhes bibliográficos
Main Authors: Gonzalez-Scarano, F, Janssen, R S, Najjar, J A, Pobjecky, N, Nathanson, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC254862/
https://ncbi.nlm.nih.gov/pubmed/3889368
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