Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats

Heterodimerization of G-protein coupled receptors can alter receptor pharmacology. ET(A) and ET(B) receptors heterodimerize when co-expressed in heterologous expression lines. We hypothesized that ET(A) and ET(B) receptors heterodimerize and pharmacologically interact in vena cava from wild-type (WT...

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Hlavní autoři: Thakali, Keshari, Galligan, James J., Fink, Gregory D., Gariepy, Cheryl E., Watts, Stephanie W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529478/
https://ncbi.nlm.nih.gov/pubmed/18485831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2008.03.005
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