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A powerful method combining homologous recombination and site-specific recombination for targeted mutagenesis in Drosophila

Gene targeting provides a powerful tool for dissecting gene function. However, repeated targeting of a single locus remains a practice mostly limited to unicellular organisms that afford simple targeting methodologies. We developed an efficient method to repeatedly target a single locus in Drosophil...

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Hlavní autoři: Gao, Guanjun, McMahon, Conor, Chen, Jie, Rong, Yikang S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529331/
https://ncbi.nlm.nih.gov/pubmed/18772376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805843105
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