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Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease
Cellular localization determines whether the serine protease HtrA2 exerts pro- or antiapoptotic functions. In contrast to the well-characterized proapoptotic function of cytosolic HtrA2, mechanisms underlying the mitochondrial protective role are poorly understood. Mpv17l is a transmembrane protein...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529330/ https://ncbi.nlm.nih.gov/pubmed/18772386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801146105 |
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