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Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores

BACKGROUND: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic data. Two statistical models have been proposed. In the asymptotic limit of long sequences, the Karlin-Altschul model is b...

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Hlavní autoři: Bastien, Olivier, Maréchal, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529321/
https://ncbi.nlm.nih.gov/pubmed/18687111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-332
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