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An amphioxus orthologue of the estrogen receptor that does not bind estradiol: Insights into estrogen receptor evolution
BACKGROUND: The origin of nuclear receptors (NRs) and the question whether the ancestral NR was a liganded or an unliganded transcription factor has been recently debated. To obtain insight into the evolution of the ligand binding ability of estrogen receptors (ER), we comparatively characterized th...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529310/ https://ncbi.nlm.nih.gov/pubmed/18655705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-219 |
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