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Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE

BACKGROUND: It has been shown previously that human monocytes fed with haemozoin (HZ) or trophozoite-parasitized RBCs displayed increased matrix metalloproteinase-9 (MMP-9) enzyme activity and protein/mRNA expression and increased TNF production, and showed higher matrix invasion ability. The presen...

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Detalhes bibliográficos
Main Authors: Prato, Mauro, Gallo, Valentina, Giribaldi, Giuliana, Arese, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529304/
https://ncbi.nlm.nih.gov/pubmed/18710562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-157
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