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Transduction of Basolateral-to-Apical Signals across Epithelial Cells: Ligand-stimulated Transcytosis of the Polymeric Immunoglobulin Receptor Requires Two Signals

Transcytosis of the polymeric immunoglobulin receptor (pIgR) is stimulated by binding of its ligand, dimeric IgA (dIgA). During this process, dIgA binding at the basolateral surface of the epithelial cell transmits a signal to the apical region of the cell, which in turn stimulates the transport of...

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Bibliographic Details
Main Authors: Luton, Frédéric, Mostov, Keith E.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25293/
https://ncbi.nlm.nih.gov/pubmed/10233153
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