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A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor

Polymeric immunoglobulin A (pIgA) transcytosis, mediated by the polymeric immunoglobulin receptor (pIgR), is a central component of mucosal immunity and a model for regulation of polarized epithelial membrane traffic. Binding of pIgA to pIgR stimulates transcytosis in a process requiring Yes, a Src...

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Main Authors: Su, Tao, Bryant, David M., Luton, Frédéric, Vergés, Marcel, Ulrich, Scott M., Hansen, Kirk C., Datta, Anirban, Eastburn, Dennis J., Burlingame, Alma L., Shokat, Kevan M., Mostov, Keith E.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072784/
https://ncbi.nlm.nih.gov/pubmed/21037565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2118
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