MicroRNAs can regulate human APP levels

A number of studies have shown that increased APP levels, resulting from either a genomic locus duplication or alteration in APP regulatory sequences, can lead to development of early-onset dementias, including Alzheimer's disease (AD). Therefore, understanding how APP levels are regulated coul...

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Autors principals: Patel, Neha, Hoang, David, Miller, Nathan, Ansaloni, Sara, Huang, Qihong, Rogers, Jack T, Lee, Jeremy C, Saunders, Aleister J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529281/
https://ncbi.nlm.nih.gov/pubmed/18684319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-3-10
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