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Polyomavirus late leader region serves an essential spacer function necessary for viability and late gene expression.

All three polyomavirus late mRNAs contain multiple tandem copies of the same nontranslated 57-nucleotide sequence, the late leader, at their 5' ends. We show here that a polyoma variant (ALM) lacking 48 central bases of the 57-base leader unit is nonviable by plaque assay and by a new method fo...

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Detalhes bibliográficos
Main Authors: Adami, G R, Carmichael, G G
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC252927/
https://ncbi.nlm.nih.gov/pubmed/3009856
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