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Polyomavirus late leader region serves an essential spacer function necessary for viability and late gene expression.

All three polyomavirus late mRNAs contain multiple tandem copies of the same nontranslated 57-nucleotide sequence, the late leader, at their 5' ends. We show here that a polyoma variant (ALM) lacking 48 central bases of the 57-base leader unit is nonviable by plaque assay and by a new method for tes...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Adami, G R, Carmichael, G G
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252927/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3009856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.58.2.417-425.1986
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