High Density Lipoprotein-associated Sphingosine 1-Phosphate Promotes Endothelial Barrier Function

High density lipoproteins (HDL) are major plasma carriers of sphingosine 1-phosphate (S1P). Here we show that HDL increases endothelial barrier integrity as measured by electric cell substrate impedance sensing. S1P was implicated as the mediator in this process through findings showing that pertuss...

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Autors principals: Argraves, Kelley M., Gazzolo, Patrick J., Groh, Eric M., Wilkerson, Brent A., Matsuura, Bryan S., Twal, Waleed O., Hammad, Samar M., Argraves, W. Scott
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529014/
https://ncbi.nlm.nih.gov/pubmed/18606817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801214200
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