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Switching of G-protein Usage by the Calcium-sensing Receptor Reverses Its Effect on Parathyroid Hormone-related Protein Secretion in Normal Versus Malignant Breast Cells

The calcium-sensing receptor (CaR) is a G-protein-coupled receptor that signals in response to extracellular calcium and regulates parathyroid hormone secretion. The CaR is also expressed on normal mammary epithelial cells (MMECs), where it has been shown to inhibit secretion of parathyroid hormone-...

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Autors principals: Mamillapalli, Ramanaiah, VanHouten, Joshua, Zawalich, Walter, Wysolmerski, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528989/
https://ncbi.nlm.nih.gov/pubmed/18621740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801738200
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