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HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase–dependent mechanism

Plasmacytoid DCs (pDCs) have been implicated as crucial cells in antiviral immune responses. On recognizing HIV, they become activated, secreting large amounts of IFN-α and inflammatory cytokines, thereby potentiating innate and adaptive antiviral immune responses. Here, we have shown that HIV-stimu...

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Detalhes bibliográficos
Main Authors: Manches, Olivier, Munn, David, Fallahi, Anahita, Lifson, Jeffrey, Chaperot, Laurence, Plumas, Joel, Bhardwaj, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528911/
https://ncbi.nlm.nih.gov/pubmed/18776940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34823
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