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Isolation of an MH2 retrovirus mutant temperature sensitive for macrophage but not fibroblast transformation.

A conditional mutant of the MH2 avian retrovirus, termed ts41MH2, was isolated. Unlike wtMH2, ts41MH2 permitted transformed macrophages to differentiate during a 5- to 7-day temperature shift from 37 to 42 degrees C. Mutant-infected cells incubated at 42 degrees C exhibited a flattened morphology an...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
1. Verfasser: Palmieri, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1986
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3005642/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.58.1.134-141.1986
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