Isolation of an MH2 retrovirus mutant temperature sensitive for macrophage but not fibroblast transformation.
A conditional mutant of the MH2 avian retrovirus, termed ts41MH2, was isolated. Unlike wtMH2, ts41MH2 permitted transformed macrophages to differentiate during a 5- to 7-day temperature shift from 37 to 42 degrees C. Mutant-infected cells incubated at 42 degrees C exhibited a flattened morphology an...
Enregistré dans:
| Publié dans: | J Virol |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3005642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.58.1.134-141.1986 |
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