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One-Pot Synthesis of Trisubstituted Conjugated Dienes via Sequential Suzuki-Miyaura Cross-Coupling with Alkenyl- and Alkyltrifluoroborates

The sequential, stereoselective disubstitution of 1,1-dibromoalkenes using a variety of alkenyltrifluoroborates followed by alkyltrifluoroborates in the presence of Pd(PPh(3))4 is described. This synthetic method proceeds smoothly in one pot under mild reaction conditions to provide the correspondin...

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Autors principals: Molander, Gary A., Yokoyama, Yasuo
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528285/
https://ncbi.nlm.nih.gov/pubmed/16526802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052636k
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