Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression.
H2dl808 is a defective deletion mutant of human adenovirus 2 lacking most of transcriptional early region 4. Although the mutant can be grown in the complementing cell line W162, it is defective in human cell lines normally used to propagate adenovirus. In such nonpermissive cells, H2dl808 exhibits...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252812/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3485200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.3.833-838.1986 |
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